Publications by authors named "A Strasser"
Article Synopsis
- Noncentrosymmetric two-dimensional superconductors like few-layer T_{d}-MoTe_{2} exhibit unique superconducting properties, including upper critical fields exceeding the Pauli limit by up to 600%.
- The enhancement of these properties is still debated, with theories suggesting influences from either spin-orbit parity coupling or tilted Ising spin-orbit coupling.
- In bilayer T_{d}-MoTe_{2}, experiments show superconductivity has a twofold symmetry influenced by magnetic and electric fields, and findings support tilted Ising spin-orbit coupling as the main mechanism.
The tumour suppressor gene p53 is one of the most frequently mutated genes in lung cancer and these defects are associated with poor prognosis, albeit some debate exists in the lung cancer field. Despite extensive research, the exact mechanisms by which mutant p53 proteins promote the development and sustained expansion of cancer remain unclear. This review will discuss the cellular responses controlled by p53 that contribute to tumour suppression, p53 mutant lung cancer mouse models and characterisation of p53 mutant lung cancer.
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- Venetoclax is a novel drug that improves outcomes for chronic lymphocytic leukemia (CLL) patients, showing that early treatment response can predict long-term success.
- Researchers used mass cytometry to analyze blood samples from CLL patients and found that venetoclax significantly reduced various CLL cell subpopulations while increasing survival proteins in the remaining cells.
- The study suggests that CLL cells quickly adapt to therapies through survival signals like the B-cell activating factor (BAFF), indicating that combining treatments might lead to more effective and lasting results.
Article Synopsis
- Scientists have learned that controlled cell death is important in fighting cancer.
- Researchers are finding new ways to use special drugs called BH3-mimetics to help kill cancer cells.
- There are still challenges to overcome in using these drugs effectively, and scientists are working hard to solve these problems.
Introduction: IQOS, a heated tobacco product (HTP), is among a growing number of noncombustible nicotine delivery alternatives marketed to people who smoke combustible cigarettes and are interested in less harmful alternatives. Little is known regarding whether IQOS use and IQOS-associated effects impact motivation to quit cigarette smoking.
Methods: Non-treatment-seeking adult daily smokers (n = 87) completed a within-subjects study consisting of a baseline ad-lib smoking period (days 1-5), two laboratory visits (days 6-7) involving IQOS exposure, and a two-week period where participants were instructed to switch from smoking cigarettes to using IQOS (days 8-21).