Publications by authors named "A Stintzi"
Background: Dietary exclusion of lactose from patients with inflammatory bowel disease (IBD) persists with speculation that deleterious effects are mediated through intestinal microbes.
Objectives: To compare IBD characteristics and changes in the intestinal microbiome (IM) at diagnosis in children with and without lactose malabsorption (LM).
Methods: A cross-sectional cohort of children (8-17 y of age) diagnosed with Crohn's disease [n = 149 (63%)] or ulcerative colitis (n = 86) that had undergone lactose breath hydrogen testing was evaluated.
Article Synopsis
- - Mother's milk has diverse bacterial communities, and this study investigates how these bacteria affect the gut microbiota of very-low-birth-weight (VLBW) infants during hospitalization, analyzing 94 mother-infant pairs and 422 milk-stool samples.
- - Approximately 30%-40% of the bacterial types found in the infants' guts are also present in the mother's milk, showing a direct link between milk consumption and gut microbiota development in VLBW infants, influenced by feeding practices and antibiotic use.
- - The findings suggest that the microbiota in mother's milk plays a significant role in shaping the gut bacteria of VLBW infants, indicating that specific milk bacteria and their interactions are important for gut colonization.
Article Synopsis
- The study looked at how kids with Inflammatory Bowel Disease (IBD) participated in two clinical trials that tested new food treatments.
- Researchers talked to 42 kids and their caregivers to understand how these treatments fit into their daily lives and any challenges they faced.
- Three main themes came up: the impact of living with IBD, difficulties with trial activities, and how these activities mixed with school and home life.
Article Synopsis
- * The article highlights significant research questions surrounding plant proteolysis, focusing on various aspects such as the cell cycle, DNA damage response, and metabolic signaling.
- * Experts discuss important pathways and mechanisms, including signals for protein degradation and plant responses to environmental challenges, aiming to inspire further research in these areas.
There is currently a growing interest in the use of nutraceuticals as a means of preventing the development of complex diseases. Given the considerable health potential of milk-derived peptides, the aim of this study was to investigate the protective effects of glycomacropeptide (GMP) on metabolic syndrome. Particular emphasis was placed on the potential mechanisms mitigating cardiometabolic disorders in high-fat, high-fructose diet-fed mice in the presence of GMP or Bipro, an isocaloric control.
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