Publications by authors named "A Stasiak-Barmuta"

Unlabelled: Vaccination has been considered the most crucial defence against viral infections, including SARS-CoV-2. Numerous reports have demonstrated the effectiveness of the above vaccines in oncological patients. It has also been proven that, apart from vaccinations and oncological therapy, the course of the cancer process itself influences the magnitude of the humoral response, especially in people after infection with SARS-CoV-2.

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The Coronavirus Disease 2019 (COVID-19) pandemic has had a significant impact on global healthcare, with high mortality and severe complications remaining a major concern. Understanding the predictors of COVID-19 severity may improve patient management and outcomes. While considerable research has focused on the pathogenesis of the virus and vaccine development, the identification of reliable demographic, clinical and laboratory predictors of severe disease remains critical.

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The Coronavirus Disease 2019 (COVID-19) has caused a global health crisis. Mortality predictors in critically ill patients remain under investigation. A retrospective cohort study included 201 patients admitted to the intensive care unit (ICU) due to COVID-19.

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Article Synopsis
  • Sixty COVID-19 patients were divided into mild and severe groups to study their immune responses using flow cytometry and blood tests.
  • In the mild group, there was a notable increase in certain immune cell markers, indicating a stronger immune activation compared to the severe group, which exhibited lower CD4 cell counts but significant migration and proliferation of other lymphocytes.
  • The findings suggest that the mild cases might have better cellular immunity, which could imply that vaccination could help reduce the severity of COVID-19 and lower the risk of long-term complications.
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Introduction: In case of newly emerging pathogens, convalescent plasma (CP) is often the only early available treatment option. It has been shown that different IgG subclasses contribute differently to CP neutralizing activity. As CP donors often have a risk profile like first-time donors, especially with respect to window-period viral transmission, pathogen reduction (PR) could mitigate that risk.

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