Detection of Putative Virulence Genes , , and in Isolates from Austrian Patients.

In , two genes ( and ) have been found to be associated with the invasion of the amniotic cavity, and a single gene () to be associated with intra-amniotic infections and a high risk of preterm birth. The syntopic presence of spp. in the same patient has been shown to correlate with the absence of in .

The Prevalence of Genital Mycoplasmas and Coinfection with in Female Patients in Vienna, Austria.

causes trichomoniasis, the most recurrent sexually transmitted infection (STI) worldwide. Genital mycoplasmas, not considered STI agents, are frequently isolated from the female genital tract. A symbiosis between species and has been described.

Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases.

ABCB4 (ATP-binding cassette subfamily B member 4) is a hepatocanalicular floppase involved in biliary phosphatidylcholine (PC) secretion. Variations in the ABCB4 gene give rise to several biliary diseases, including progressive familial intrahepatic cholestasis type 3 (PFIC3), an autosomal recessive disease that can be lethal in the absence of liver transplantation. In this study, we investigated the effect and potential rescue of ten ABCB4 missense variations in NBD1:NBD2 homologous positions (Y403H/Y1043H, K435M/K1075M, E558K/E1200A, D564G/D1206G and H589Y/H1231Y) all localized at the conserved and functionally critical motifs of ABC transporters, six of which are mutated in patients.

Characterisation of Isolates Collected from Patients in Vienna between 2019 and 2021.

(TV) is the causative agent of trichomoniasis, the most common nonviral sexually transmitted disease. TV can carry symbionts such as virus (TVV) or . Four distinct strains of TV are known: TVV1, TVV2, TVV3, and TVV4.

The Changing Spectrum of Sexually Transmitted Infections in Europe.

As long as 400 years ago, syphilitic ulcers and gonococcal discharge were observed in connection with sexual intercourse. War, poverty, and lack of efficient therapeutic options led to a high incidence of venereal diseases, many of which had devastating outcomes. This situation continued until the beginning of the 20th century, when the microbial aetiology of venereal diseases was discovered.