Publications by authors named "A Spagnolo"
Uveitis in paediatric Behçet disease: a large multicentric Italian cohort.
Ther Adv Musculoskelet Dis
December 2024
Background: Behçet disease (BD) is a rare disease in childhood and its uveitis may lead to blindness if not properly treated.
Objectives: We aim to describe a cohort of paediatric BD patients with uveitis.
Design: This is a multicentric retrospective study.
(MC), a member of the complex, can cause infections in patients after open-heart surgery due to contaminated heater-cooler units (HCUs). The transmission route of HCU-related MC infection is non-inhalational, and infection can occur in patients without previously known immune deficiency. Patients may develop endocarditis of the prosthetic valve, infection of the vascular graft, and/or manifestations of disseminated mycobacterial infection (splenomegaly, arthritis, hepatitis, nephritis, myocarditis, etc.
View Article and Find Full Text PDFMammographic density (MD) assessment is subject to inter- and intra-observer variability. An automated method, such as Quantra software, could be a useful tool for an objective and reproducible MD assessment. Our purpose was to evaluate the performance of Quantra software in assessing MD, according to BI-RADS Atlas Fifth Edition recommendations, verifying the degree of agreement with the gold standard, given by the consensus of two breast radiologists.
View Article and Find Full Text PDFArticle Synopsis
- PFAPA is a common childhood condition characterized by symptoms like periodic fever and sore throat, which can affect the quality of life for both children and their families.
- A study evaluated the effectiveness of Streptococcus Salivarius K12 (SSK12) in reducing the frequency and severity of febrile episodes in 117 PFAPA patients aged 6 months to 9 years.
- Results showed that after six months of SSK12 treatment, the recurrence of febrile episodes increased significantly from every 26.1 days to every 70 days, along with reductions in fever duration and maximum temperature, as well as a decrease in related symptoms like throat infections and mouth ulcers.
Background: Complete removal of cardiac implantable electronic devices (CIEDs) is recommended in patients with CIED infections, including both systemic and localized pocket infection. The aim of the study was to provide an up-to-date and comprehensive assessment of evidence relating to the effect of complete CIED extraction in patients with a CIED infection.
Methods: We performed a systematic review and meta-analysis of studies reporting short- and mid-term outcomes in patients who had a device infection or infective endocarditis (IE) and underwent complete removal of the cardiac device (generator and leads) compared to those who received conservative therapy (no removal, partial removal, local antibiotic infiltration or isolated antibiotic therapy).