Publications by authors named "A Soucy"

Objective: To examine awareness, information-seeking, and use of MyPlate among US adults with young children.

Design: Secondary analysis of cross-sectional data from the 2015-2018 National Health and Nutrition Examination Survey (NHANES).

Participants: US adults aged 18-45 years with children ≤5 years.

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Recovery from respiratory pneumococcal infections generates lung-localized protection against heterotypic bacteria, mediated by resident memory lymphocytes. Optimal protection in mice requires re-exposure to pneumococcus within days of initial infection. Serial surface marker phenotyping of B cell populations in a model of pneumococcal heterotypic immunity revealed that bacterial re-exposure stimulates the immediate accumulation of dynamic and heterogeneous populations of B cells in the lung, and is essential for the establishment of lung resident memory B (B) cells.

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Article Synopsis
  • Loss of RAB27A affects cardiovascular function and metabolism, as evidenced by changes in body weight, glucose handling, and vasoreactivity in mice.
  • Male mice lacking RAB27A experienced more pronounced cardiovascular issues, including increased vasoconstriction and age-related cardiomyopathy, compared to their wild-type counterparts.
  • Proteomic analysis indicated significant differences in the tissue signatures of male null mice related to cardiovascular and metabolic phenotypes, highlighting a gender-related impact of RAB27A loss.
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This study presents an integrated approach to understanding fluid dynamics in Microfluidic Paper-Based Analytical Devices (µPADs), combining empirical investigations with advanced numerical modeling. Paper-based devices are recognized for their low cost, portability, and simplicity and are increasingly applied in health, environmental monitoring, and food quality analysis. However, challenges such as lack of flow control and the need for advanced detection methods have limited their widespread adoption.

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