Publications by authors named "A Soos"
Enhancing risk stratification models in localized prostate cancer by novel validated tissue biomarkers.
Prostate Cancer Prostatic Dis
November 2024
Background: Localized prostate cancer (PCa) is a largely heterogeneous disease regarding its clinical behavior. Current risk stratification relies on clinicopathological parameters and distinguishing between indolent and aggressive cases remains challenging. To improve risk stratification, we aimed to identify new prognostic markers for PCa.
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- - The bursa of Fabricius (BF) is a crucial organ in birds for B-cell development, arising from the cloaca during embryonic growth.
- - Researchers found that specific precursors for B cells, macrophages, and dendritic cells migrate to the BF, with a new cell type, EIV-E12+, playing a key role in initiating the formation of lymphoid follicles.
- - Experiments with chick-duck and chick-quail combinations indicate that EIV-E12+ cells act as transient inducers for lymphoid follicle formation, but they aren't direct precursors of B or dendritic cells.
Background: Tolerance of plants towards selenium, a non-essential microelement for higher plants, is a key issue when designing either the indirect (selenium-depletion from highly seleniferous soils) or directed (selenized feed production) enrichment of selenium in forages. Alfalfa (Medicago sativa L.), the well-known forage crop of the Fabaceae family, has been gaining considerable interest due to its application as a green manure, as a cover crop, or in soil remediation by nitrogen fixation.
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- This review explores the gut-lung axis, highlighting its anatomy, function, and clinical relevance, focusing on how the gastrointestinal and respiratory systems communicate and maintain balance.
- It emphasizes the role of the gut microbiome and mucosa-associated lymphoid tissue (MALT) in immune responses, linking issues like "leaky gut" to systemic inflammation and respiratory problems.
- The review also addresses the significance of the gut-lung axis in cancer, specifically lung cancer, advocating for interdisciplinary research to improve our understanding and treatment approaches in health and disease.