Publications by authors named "A Sonaglioni"

Background: Gestational diabetes mellitus (GDM) is the most common complication in pregnancy, representing a serious risk for the mother and fetus. Identifying new biomarkers to ameliorate the screening and improving GDM diagnosis and treatment is crucial. During the last decade, a few studies have used speckle tracking echocardiography (STE) for assessing the myocardial deformation properties of fetuses (FGDM) and infants (IGDM) of GDM women, providing not univocal results.

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  • * A total of eight studies involving 303 PE patients and 498 healthy controls showed that MVP prevalence was significantly higher in PE individuals (40.6%) than in controls (12.8%), with an odds ratio of 5.80 indicating a strong association.
  • * Subgroup analysis revealed that MVP prevalence was about three times higher in PE children and adolescents compared to PE adults, and the overall results showed high consistency with no significant publication bias.
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  • A systematic review examined left atrial mechanics in patients with atrial fibrillation (AF) about to undergo electrical cardioversion (ECV), focusing on the effect of AF on left atrial reservoir strain (LASr).
  • The analysis included 12 studies with a total of 880 patients, revealing a high ECV success rate of 91.5%, but highlighted that 35.2% of patients experienced AF recurrence within a median follow-up of 5.4 months.
  • Key findings indicated that a lower LASr before ECV was linked to higher chances of cardioversion failure and AF recurrence, suggesting that measuring LASr could help predict AF relapse and assess thromboembolic risk in these patients. *
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Background: During the last two decades, a few studies have evaluated the common carotid artery (CCA) intima-media thickness (IMT) in women with previous history of pre-eclampsia (pPE) in comparison to women with uncomplicated pregnancies, providing not univocal results. This systematic review and meta-analysis has been designed to summarize the main findings of these studies and to examine the overall influence of pPE on CCA-IMT.

Methods: All studies assessing CCA-IMT in pPE women in comparison to women who had uncomplicated pregnancies, selected from PubMed and EMBASE databases, were included.

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  • - The systematic review analyzed 21 echocardiographic studies to estimate the prevalence of mitral valve prolapse (MVP), finding an overall MVP prevalence of 4.9% across various populations.
  • - Older studies (1976-1998) showed a higher MVP prevalence (7.8%), while more recent studies (1999-2021) reported a lower prevalence (2.2%), likely due to differences in diagnostic criteria and potential biases.
  • - MVP is generally associated with a low risk of significant complications, although it can be linked to mild mitral regurgitation and minor heart abnormalities, and it occurs less frequently in the general community.
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