Publications by authors named "A Somigliana"
Article Synopsis
- - Giant cell interstitial pneumonia (GIP) is a serious lung disease related to exposure to hard metals like tungsten, typically found in industrial tools, but it can also occur without clear exposure history.
- - In a study of five patients with GIP, researchers used advanced techniques to identify metal dust and asbestos in lung samples, finding trace amounts of tungsten and asbestos fibers associated with severe lung damage.
- - The results suggest that other factors beyond hard metal exposure might contribute to GIP's development, hinting at a complex immune mechanism that could explain its recurrence in lung transplants.
Objectives: In Italy, the highest pleural cancer mortality and incidence have been observed among Italian regions where the 2 largest Italian shipyards were (and are) located. The objective of this study was to assess the exposure-response relationship for mesothelioma among male workers employed in the Monfalcone, Italy, shipyard.
Methods: We conducted a necropsy-based case-control study.
Objectives: The work shows the effect of counting rules, such as analysis magnification and asbestos fiber dimension to be count (with length ≥5 µm or also asbestos fibers with length <5 µm) in the lung asbestos fiber burden analysis for legal medicine evaluations.
Methods: On the same lung tissue samples, two different analyses were carried out to count any asbestos fibers with length ≥1 µm and with length ≥5 µm. Results of the amphibole burden of the two analyses were compared by linear regression analysis on log10-transformed values.
Introduction: Malignant pleural mesothelioma is an asbestos-related disease with poor survival. The prognostic role of histologic subtype is well established. Some studies (without a biological hypothesis) suggested that higher asbestos lung burden is associated with reduced survival.
View Article and Find Full Text PDFIs Mesothelioma Unrelated to the Lung Asbestos Burden? Comment on Visonà et al. Inorganic Fiber Lung Burden in Subjects with Occupational and/or Anthropogenic Environmental Asbestos Exposure in Broni (Pavia, Northern Italy): An SEM-EDS Study on Autoptic Samples. 2021, , 2053.
Int J Environ Res Public Health
July 2021
We read with interest the report by Visonà and coworkers on the lung asbestos fiber burden in an autopsy series of decedents from mesothelioma (MM: 59 cases) and individuals who "suffered from asbestosis and died of its complications" (13 cases) [...
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