ST-elevation myocardial infarction incidence in a high-risk seismic zone.

Introduction: Earthquakes are unpredictable natural events that can elicit acute physiological responses, potentially triggering cardiovascular events. This study investigates the association between seismic activity and ST-elevation myocardial infarction (STEMI) admissions in a tertiary care hospital in an earthquake-prone region over 19 years.

Methods: We analyzed STEMI admissions at a tertiary center in Mexico City from October 2005 to August 2024.

Multiscale footprints reveal the organization of cis-regulatory elements.

Cis-regulatory elements (CREs) control gene expression and are dynamic in their structure and function, reflecting changes in the composition of diverse effector proteins over time. However, methods for measuring the organization of effector proteins at CREs across the genome are limited, hampering efforts to connect CRE structure to their function in cell fate and disease. Here we developed PRINT, a computational method that identifies footprints of DNA-protein interactions from bulk and single-cell chromatin accessibility data across multiple scales of protein size.

Vesalius and His Manikin: An Enduring Influence on Modern Anatomic Teaching.

Anatomic teaching has long informed surgical knowledge, experience, and skills. One tool for teaching that emerged during the Renaissance was the fugitive anatomic sheet, which used flap layers to reveal different levels of anatomy. In 1538, Vogtherr introduced the first fugitive sheets, which included illustrations of male and female figures with a torso paper flap that, when lifted, revealed the internal organs in a cartoonish style.

An update on the ocular manifestations of dengue.

Dengue is the most common arboviral disease. It is typically spread by the bite of an infected female or mosquitoes. Dengue is endemic in subtropical and tropical regions, but its geographic reach keeps expanding.

Factors Affecting Growth and Survival of in Onion Extracts and Onion Bulbs.

This study investigated the survival and growth of in onion extracts and bulbs. The inhibition or retardation of growth by extracts of red, white, and yellow onions was tested against the onion germplasm and exposure to different light spectra during curing. Separately, survival of Newport was tested on red, white, and yellow onion bulbs on the external and internal onion layers with a syringe and needle.