Histologic margin status is a predictor of relapse in lentigo maligna melanoma.

Background: Most surgical margins for lentigo maligna melanomas reported in the literature are clinical and not histologic.

Objectives: We sought to determine whether histologic margin status is an independent predictor of progression.

Methods: Clinicopathologic information of 268 invasive lentigo maligna melanomas diagnosed from 1990-2019 were analyzed.

Early Detection and Prognostic Assessment of Cutaneous Melanoma: Consensus on Optimal Practice and the Role of Gene Expression Profile Testing.

Importance: Therapy for advanced melanoma has transformed during the past decade, but early detection and prognostic assessment of cutaneous melanoma (CM) remain paramount goals. Best practices for screening and use of pigmented lesion evaluation tools and gene expression profile (GEP) testing in CM remain to be defined.

Objective: To provide consensus recommendations on optimal screening practices and prebiopsy diagnostic, postbiopsy diagnostic, and prognostic assessment of CM.

Predawn leaf conductance depends on previous day irradiance but is not related to growth in aspen saplings grown under artificially manipulated air humidity.

Recent studies have suggested that predawn stomatal opening may enhance early-morning photosynthesis (A) and improve the relative growth rate of trees. However, the causality between night-time stomatal conductance, A, and tree growth is disputable because stomatal opening in darkness can be mediated by previous day photosynthate loads and might be a consequence of growth-related processes like dark respiration (R). To identify linkages between night-time leaf conductance (gl_night), A, R, and tree growth, we conducted an experiment in hybrid aspen saplings grown under different air relative humidity (RH) conditions and previous day irradiance level (IR_pday).