Publications by authors named "A Smail"

Article Synopsis
  • The study identifies genetic factors linked to palmoplantar pustulosis (PPP) and explores how smoking may influence the disease.
  • Researchers conducted a large-scale genetic analysis and discovered that PPP is distinct from plaque psoriasis but associated with certain genetic loci, particularly linked to immune response.
  • The findings suggest that smoking plays a causal role in the disease's development and highlight the involvement of specific immune pathways in PPP pathology.
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Objective: Among specific autoantibodies in DM, the anti-small ubiquitin-like modifier activating enzyme (SAE) antibody is rare. We aim to describe the clinical characteristics, cancer prevalence, and muscle pathology of anti-SAE-positive DM.

Methods: Patients with a diagnosis of DM and sera positive for the anti-SAE antibody were recruited from 19 centres in this retrospective observational study.

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Cutaneous involvement in multiple myeloma with extramedullary disease is rare. We report the case of a refractory multiple myeloma patient who developed a cutaneous lesion. Histopathology revealed dermal immature plasma cell infiltrate with a lack of CD138 expression.

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Article Synopsis
  • A study was conducted to compare the diagnostic effectiveness of Fluorodesoxyglucose Positron Emission Tomography (PET/CT) with Chest-Abdomen-Pelvis CT (CAPCT) in patients suffering from fever of unknown origin (FUO), inflammation of unknown origin (IUO), and episodic fever of unknown origin (EFUO).
  • The trial included 103 patients from 7 French University Hospital centers between 2008 and 2013, assessing diagnostic orientation (DO), diagnostic contribution (DC), and time for diagnosis.
  • Results indicated that PET/CT significantly outperformed CAPCT in DO (28.2% vs. 7.8%), DC (19.4% vs.
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