[Disseminated interstitial lung lesions in Lung Diseases Clinic patients].

The large number of diseases with interstitial lesions in the lungs needs numerous expensive and complicated examinations for differential diagnosis. These difficulties and increasing number of patients made us to look for possibilities to facilitate diagnosis. In 103 patients with diagnosed disease with disseminated lung lesions, the age and gender, vital capacity of the lungs, arterial blood gases pressure, the number of lymphocytes in peripheral blood were assessed.

[The frequency of atopy in lung cancer patients].

The controversial opinions on adverse correlation between atopy and incidence of lung cancer made us to undertake the research in that field in patients, treated in Department of Lung Diseases of University School of Medicine in Bydgoszcz. In 45 histologically diagnosed lung cancer patients in III and IV stage of the disease the tendency to atopy was assessed. In above mentioned patients the serum level of total IgE, the number of eosinophyls in peripheral blood and skin tests with popular allergens such as: home-dust, feather, grass particles, fungus and mould.

[The quality of life after chemotherapy in advanced non-small cell lung cancer patients].

The intensity of complains, short survival and great number of patients makes many oncologists to apply chemotherapy in advanced non-small cell lung cancer/NSCLC/. The achieved median duration of life after chemotherapy was 6 to 12 month. From the other hand non small cell lung cancer chemotherapy is a big burden even to healthy persons.

[Analysis of circumstances of the development of chronic bronchitis in patients treated at Bydgoszcz Lung Disease Clinic in 1993-1996].

The fact, that more than 10% people suffer from COPD /chronic obstructive pulmonary disease/, that number of COPD patients increases rapidly all over the world, and at the moment COPD is one from four the most frequent cause of death, makes us to search for effective methods of prevention and treatment. The number and variety of factors cooperating in pathogenesis and development of the disease in contrast to poor knowledge of them was the reason, that the retrospective analysis of some factors of 300 COPD patients, treated in our Clinic from severe exacerbations was carried out. There were analysed the following factors; age, gender, body mass index, profession, the length and duration of the disease, incidence of exacerbations and habits; alcohol drinking and cigarette smoking.

Evaluation of immunophenotype of lymphoid cells isolated from malignant pleural effusions.

Lymphoid cells, isolated from malignant pleural effusions and collected from patients bearing primary lung carcinoma, were examined by means of indirect immunofluorescence and a panel of monoclonal antibodies vs several CD antigens. The percentages of CD4+ T lymphocytes were found to be significantly depressed in malignant effusions as compared to inflammatory ones. In relation to histological type of cancer it was especially evident in squamous cell and anaplastic carcinomas (small and large cell), in comparison to adenocarcinomas.