Sparing the Hippocampus in Prophylactic Cranial Irradiation Using Three Different Linear Accelerators: A Comparative Study.

Hippocampus protection, as an organ at risk in brain radiotherapy, might protect patients' quality of life. Prophylactic cranial irradiation (PCI) has been used traditionally in small cell lung cancer (SCLC) patients as it increases survival. This study aimed to discover the contributing parameters for a successful PCI with simultaneous protection of the hippocampus by using three different treatment machines.

Dose optimization of 2D X-ray image acquisition protocols in image-guided radiotherapy.

Purpose: In contemporary radiotherapy, patient positioning accuracy relies on kV imaging. This study aims at optimizing planar kV image acquisition protocols regarding patient dose without degrading image quality.

Materials And Methods: An image quality test-object was placed in-between PMMA plates, suitably arranged to model head or pelvis.

Institutional Diagnostic Reference Levels and Peak Skin Doses in selected diagnostic and therapeutic interventional radiology procedures.

Purpose: Institutional (local) Diagnostic Reference Levels for Cerebral Angiography (CA), Percutaneous Transhepatic Cholangiography (PTC), Transarterial Chemoembolization (TACE) and Percutaneous Transhepatic Biliary Drainage (PTBD) are reported in this study.

Materials And Methods: Data for air kerma-area product (P), air kerma at the patient entrance reference point (K), fluoroscopy time (FT) and number of images (NI) as well as estimates of Peak Skin Dose (PSD) were collected for 142 patients. Therapeutic procedure complexity was also evaluated, in an attempt to incorporate it into the DRL analysis.

Determination of the glomerular filtration rate in patients with type 2 diabetes: An assessment of the agreement between Cr-EDTA plasma clearance and Tc-DTPA plasma clearance, Tc-DTPA renography and plasma creatinine prediction equation.

Aims: To investigate the agreement of glomerular filtration rate (GFR) determination between Cr-ethylenediaminetetraacetic acid (Cr-EDTA) plasma clearance (GFR) and Tc-diethylenetriaminepentaacetic acid (Tc-DTPA) plasma clearance (GFR), the Gates Tc-DTPA renographic method (GFR) and the serum creatinine Chronic Kidney Disease Epidemiology Collaboration equation (CKD-EPI, GFR) in patients with type 2 diabetes mellitus (T2DM).

Methods: Ninety-nine T2DM patients underwent GFR determinations simultaneously with Cr-EDTA and Tc-DTPA (using the slope-intercept technique and the Brochner-Mortensen correction) and also with GFR and GFR.

Results: In the comparison between GFR versus GFR, GFR and GFR, the Bland-Altman statistic provided 0.

The effect of scatter correction and radius of rotation on semiquantitative measurements in SPECT I-FP-CIT imaging. A phantom study.

Purpose: The high energy emissions of I and the suboptimal radius of rotation affect the semiquantitative measurements performed during I-FP-CIT tomographic imaging. An in-house extra low cost striatum phantom with brain and striatum compartments was constructed and was used to study the effects of Triple Energy Window scatter correction (TEW-SC) and radius of rotation on the Specific Binding Ratio (SBR) measurements.

Materials And Methods: The phantom compartments were filled with radioactive I solutions with varying concentrations, in a series of experiments.