Molecular profiling of invertebrate glia.

Caenorhabditis elegans and Drosophila melanogaster are powerful experimental models for uncovering fundamental tenets of nervous system organization and function. Findings over the last two decades show that molecular and cellular features are broadly conserved between invertebrates and vertebrates, indicating that insights derived from invertebrate models can broadly inform our understanding of glial operating principles across diverse species. In recent years, these model systems have led to exciting discoveries in glial biology and mechanisms of glia-neuron interactions.

Thermoluminescence and optically stimulated luminescence studies of Gypsum for retrospective dosimetry.

This study examines the use of gypsum for radiation dosimetry using Thermoluminescence (TL) and Optically Stimulated Luminescence (OSL) techniques. It is observed that gypsum preserves the information of radiation dose despite the loss of water upon heating in a laboratory. Deconvolution of the thermoluminescence glow curve suggests thermoluminescence glow peaks at 125, 150, 280, 320, and 440 °C.

Glia in Invertebrate Models: Insights from Caenorhabditis elegans.

Glial cells modulate brain development, function, and health across all bilaterian animals, and studies in the past two decades have made rapid strides to uncover the underlying molecular mechanisms of glial functions. The nervous system of the invertebrate genetic model Caenorhabditis elegans (C. elegans) has small cell numbers with invariant lineages, mapped connectome, easy genetic manipulation, and a short lifespan, and the animal is also optically transparent.

Epithelial UNC-23 limits mechanical stress to maintain glia-neuron architecture in C. elegans.

For an organ to maintain correct architecture and function, its diverse cellular components must coordinate their size and shape. Although cell-intrinsic mechanisms driving homotypic cell-cell coordination are known, it is unclear how cell shape is regulated across heterotypic cells. We find that epithelial cells maintain the shape of neighboring sense-organ glia-neuron units in adult Caenorhabditis elegans (C.