Publications by authors named "A Sinaniotis"
Background: Pru p 3 and Pru p 7 have been implicated as risk factors for severe peach allergy. This study aimed to establish sensitization patterns to five peach components across Europe and in Japan, to explore their relation to pollen and foods and to predict symptom severity.
Methods: In twelve European (EuroPrevall project) and one Japanese outpatient clinic, a standardized clinical evaluation was conducted in 1231 patients who reported symptoms to peach and/or were sensitized to peach.
Article Synopsis
- The study aims to understand why peanut allergy (PA) severity differs among patients by analyzing data from 393 cases, focusing on clinical profiles and predictive factors for severity.* -
- Results indicate that factors such as female sex, age of onset, and specific allergies (e.g., atopic dermatitis, latex) are linked to more severe PA, while birch pollen allergy is associated with milder cases.* -
- Although some IgE levels (like those to peanut extract and specific components) correlate with PA severity, clinical background factors remain the most effective predictors of an individual patient's risk for severe allergic reactions.*
Background: The heterogeneity and lack of validation of existing severity scores for food allergic reactions limit standardization of case management and research advances. We aimed to develop and validate a severity score for food allergic reactions.
Methods: Following a multidisciplinary experts consensus, it was decided to develop a food allergy severity score (FASS) with ordinal (oFASS) and numerical (nFASS) formats.
Background: Walnut allergy is common across the globe, but data on the involvement of individual walnut components are scarce.
Objectives: To identify geographical differences in walnut component sensitization across Europe, explore cosensitization and cross-reactivity, and assess associations of clinical and serological determinants with severity of walnut allergy.
Methods: As part of the EuroPrevall outpatient surveys in 12 European cities, standardized clinical evaluation was conducted in 531 individuals reporting symptoms to walnut, with sensitization to all known walnut components assessed in 202 subjects.