Publications by authors named "A Simonsson"
The aim of this study was to investigate how the propensity for aerosolisation in binary adhesive mixtures was affected by the drug load, and to determine whether these findings could be linked to different blend states. Binary blends of two different lactose carriers, each with varying size and morphology, were prepared together with budesonide. In vitro aerosolisation studies were conducted at four different pressure drops, ranging from 0.
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- The study investigates the reaction between vibronically cold NO^{+} and O^{-} at a low collision energy of about 0.1 eV, focusing on single-collision interactions.
- The reaction primarily results in the formation of three ground-state atomic fragments.
- Using product-momentum analysis, the researchers propose a two-step mechanism where the anion donates an electron, leading to an intermediate Rydberg state of NO that eventually breaks apart.
Article Synopsis
- The study focuses on the mutual neutralization reaction between hydronium (HO) and hydroxide (OH) ions, which is a basic yet not well-understood chemical process.
- Using advanced imaging techniques in a cryogenic ion storage facility, researchers observed the products formed during these reactions at low collision energies.
- The findings reveal that most of the reactions involve electron-transfer mechanisms, while some also involve proton transfer, helping to create a basis for future modeling of charge-transfer processes.
We have studied the stability of the smallest long-lived all carbon molecular dianion (C_{7}^{2-}) in new time domains and with a single ion at a time using a cryogenic electrostatic ion-beam storage ring. We observe spontaneous electron emission from internally excited dianions on millisecond timescales and monitor the survival of single colder C_{7}^{2-} molecules on much longer timescales. We find that their intrinsic lifetime exceeds several minutes-6 orders of magnitude longer than established from earlier experiments on C_{7}^{2-}.
View Article and Find Full Text PDFThe objective of this investigation was to study the effect of induced vibrations on adhesive mixtures containing budesonide and salbutamol sulphate as active pharmaceutical ingredients (APIs) and InhaLac 70 as carrier. A series of adhesive mixtures with varied API concentration (1-4%) was prepared for each API. Half of the adhesive mixture was stressed on a vibrating sieve under conditions resembling hopper flow.
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