Publications by authors named "A Sili-Scavalli"
Background: Screening for latent tuberculosis infection is recommended in patients with rheumatoid arthritis (RA) starting Janus kinase inhibitors (Jaki). Interferon (IFN)-gamma release assays (IGRAs) are increasingly used for this purpose. Jaki tend to decrease the levels of IFNs, questioning the reliability of IGRAs during treatment with these drugs.
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- This meta-analysis aimed to compare the outcomes of transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) in low-risk patients with severe aortic valve stenosis (AS).
- Results showed that TAVI had a significantly lower 30-day mortality rate and lower instances of major bleeding and acute kidney injury compared to SAVR. However, TAVI was associated with a higher risk of needing a new pacemaker and experiencing paravalvular leak.
- The study concludes that while TAVI shows advantages in some areas, it also presents risks that make further trials necessary to fully evaluate its effectiveness against traditional SAVR.
Objectives: In this longitudinal study, we assessed the role of musculoskeletal ultrasound (US) in predicting the efficacy of JAK inhibitors (JAKi) in rheumatoid arthritis (RA) patients.
Methods: We enrolled RA patients starting baricitinib or tofacitinib. All patients were evaluated at baseline and after 4, 12, 24, 48 weeks.