Simulation Studies of Dynamical Heterogeneity in a Dense Two-Dimensional Dimer-Solvent System with Obstacles.

A coarse-grained model of a two-dimensional colloidal suspension was designed. The model was athermal and, in addition, a lattice approximation was introduced. It consisted of solvent (monomer) molecules, dimer molecules, and immobile impenetrable obstacles that introduced additional heterogeneity into the system.

The Kinetics of Polymer Brush Growth in the Frame of the Reaction Diffusion Front Formalism.

We studied the properties of a reaction front that forms in irreversible reaction-diffusion systems with concentration-dependent diffusivities during the synthesis of polymer brushes. A coarse-grained model of the polymerization process during the formation of polymer brushes was designed and investigated for this purpose. In this model, a certain amount of initiator was placed on an impenetrable surface, and the "grafted from" procedure of polymerization was carried out.

Light-Controlled Anticancer Activity and Cellular Uptake of a Photoswitchable Cisplatin Analogue.

A photoactive analogue of cisplatin was synthesized with two arylazopyrazole ligands, able to undergo -/- photoisomerizations. The photoisomer showed a dark half-life of 9 days. The cytotoxicities of both photoisomers of the complex were determined in several cancer and normal cell lines and compared to that of cisplatin.

The Influence of Local Constraints on Solvent Motion in Polymer Materials.

The influence of obstacles in the form of polymer chains on the diffusion of a low-molecular-weight solvent was the subject of this research. Studies were performed by computer simulations. A Monte Carlo model-the Dynamic Lattice Liquid algorithm-based on the idea of cooperative movements was used.

Cobalt Serum Level as a Biomarker of Cause-Specific Survival among Prostate Cancer Patients.

Prostate cancer is the most common cancer diagnosed in men and the second leading cause of death in male cancer patients. The WHO suggests that cobalt is involved in the carcinogenesis of prostate cancer. There are, however, no studies associating cobalt levels and prostate cancer patient survival.