The Olive Oil Monophenolic Secoiridoid Ligstroside Aglycone Suppresses Melanoma Progression by Targeting the BRAF Signaling Pathway.

Melanoma is among the most abundant malignancies in the US and worldwide. Ligstroside aglycone (LA) is a rare extra-virgin olive oil-derived monophenolic secoiridoid with diverse bioactivities. LA dose-response screening at the NCI 60 cancer cells panel identified the high sensitivity of the Malme-3M cell line, which harbors a mutation.

Assessment of energy management and power quality improvement of hydrogen based microgrid system through novel PSO-MWWO technique.

A hybrid microgrid powered by hydrogen is an energy infrastructure that depends on hydrogen as its primary energy carrier within a localized network. This study proposed a novel bi-level optimization approach to enhance power quality and cost efficiency of the system. In the quest to improve energy management systems (EMS) and enhance power quality, a bi-level optimization approach named Particle swarm optimization-Modified water wave optimization (PSO-MWWO) has been proposed.

Non-carcinogenic health risks assessment of bioaerosols.

Bioaerosols, pose potential health risks, yet quantitative assessments of non-carcinogenic risks from bioaerosol inhalation are limited. This study introduces a novel approach for assessing non-carcinogenic health risks using bioaerosol exposure data. The method employs the Average Daily Dose and Hazard Quotient (HQ) metrics, adapted from US Environmental Protection Agency guidelines, with the Reference Dose (RfD) based on thresholds from the National Institute of Occupational Safety and Health and the American Conference of Governmental Industrial Hygienists.

Assessment of knowledge, attitudes, and practices regarding air pollution among traffic polices in Dhaka city, Bangladesh: a cross-sectional study.

Background: The increasing number of motor vehicles in Dhaka city is contributing to a rise in air pollution. Prolonged exposure to vehicle emissions has led to various health issues for everyone, but traffic policies might be particularly affected. This study aims to evaluate their knowledge, attitudes, and practices regarding air pollution, with the goal of raising awareness and promoting healthier practices to mitigate the adverse effects of pollution.