Primary and secondary prevention of cervical cancer among Italian AFAB transgender people.

Objective: Currently, available data on preventive measures for Human Papillomavirus (HPV) infection and cervical cancer in the transgender assigned female at birth (AFAB) community are extremely limited. Our aim was to analyze adherence to primary and secondary cervical cancer prevention screening programs among transgender AFAB people attending our gender clinic.

Methods: Transgender AFAB people attending our center were recruited.

The effects of nitric oxide inhibition on regional hemodynamics during hyperdynamic endotoxemia.

Objective: To determine the effect of the inhibition of nitric oxide (NO) on selective organ blood flow in endotoxin-induced sepsis.

Design: Nonrandomized, controlled experiment.

Setting: Animal research facility in Brooklyn, NY.

Nitric oxide inhibition in the treatment of the sepsis syndrome is detrimental to tissue oxygenation.

The manifestations of the septic syndrome are thought to be mediated by cytokines through their role in the production of nitric oxide (NO). It is hypothesized that the inhibition of NO production with an inhibitor such as NG-monomethyl-L-arginine (L-NMMA) may be beneficial in the treatment of septic shock. Sepsis was induced by the intravenous administration of Escherichia coli endotoxin (60 micrograms/kg) in six conditioned mongrel dogs (20-24 kg).