Effects of quetiapine on cognitive functions in schizophrenic patients: a preliminary single-trial ERP analysis.

Aim: The study aimed to explore by means of single-trial event-related potentials (ERPs), whether and how the medication change from older neuroleptics to quetiapine in schizophrenic patients led to a significant cognitive enhancement. This single-trial ERP analysis helps to investigate attention and memory processes in the single patient before and after treatment.

Patients And Methods: Thirteen schizophrenic patients (mean age: 40.