Publications by authors named "A Shipolini"
Article Synopsis
- The study assessed the external validity of the Barts Surgical Infection Risk (B-SIR) tool for predicting surgical site infections (SSI) in cardiac surgery patients compared to other risk tools, ACRI and BHIS.
- An analysis of 6,022 patients showed that B-SIR had a better predictive accuracy (AUC=0.686) for SSI than both ACRI (AUC=0.614) and BHIS (AUC=0.610).
- The findings suggest that B-SIR could be a valuable tool for routine use in clinical practice to improve risk assessment for infections after cardiac surgeries.
Purpose Of Review: Whilst abnormally increased left ventricular wall thickness is the hallmark feature of hypertrophic cardiomyopathy (HCM), anomalies of the mitral valve and supporting apparatus are well documented. This review addresses the clinical importance of mitral valve abnormalities in HCM, their mechanistic associations with symptoms, and therapeutic strategies targeting mitral valve and apparatus abnormalities.
Recent Findings: The normal mitral valve possesses anatomical features facilitating unrestricted blood flow during LV filling, preventing regurgitation during LV systole, and avoiding obstruction of LV ejection.
BACKGROUNDEpicardial adipose tissue (EAT) directly overlies the myocardium, with changes in its morphology and volume associated with myriad cardiovascular and metabolic diseases. However, EAT's immune structure and cellular characterization remain incompletely described. We aimed to define the immune phenotype of EAT in humans and compare such profiles across lean, obese, and diabetic patients.
View Article and Find Full Text PDFObjectives: The objective of this study was to develop and validate a new risk tool (Barts Surgical Infection Risk (B-SIR)) to predict surgical site infection (SSI) risk after all types of adult cardiac surgery, and compare its predictive ability against existing (but procedure-specific) tools: Brompton-Harefield Infection Score (BHIS), Australian Clinical Risk Index (ACRI), National Nosocomial Infection Surveillance (NNIS).
Study Design And Setting: Single-center retrospective analysis of prospectively collected data including 2,449 patients undergoing cardiac surgery between January 2016 and December 2017 in a European tertiary hospital. Thirty-four variables associated with SSI risk after cardiac surgery were collated from three local databases.