Publications by authors named "A Shelest"

One of the hypothesized functions of biomolecular condensates is to act as chemical reactors, where chemical reactions can be modulated, i.e., accelerated or slowed down, while substrate molecules enter and products exit from the condensate.

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The aim of the study was to determine the concentrations of inflammatory markers C-reactive protein (C-RP) and cytokines - IL-1β, IL-4 in patients with arterial hypertension (AH) and obesity. The study involved 64 patients with hypertension, who were divided into 2 groups. The first (main group) consisted of 39 patients with arterial hypertension II degree and obesity 1 st.

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The authors studied an antianginal effect of the angiotensin-converting enzyme, for which purpose they used Capoten at 75 mg daily over two weeks in 24 patients with stable functional class II-III exertional angina. Capoten was shown to be capable of reducing occurrences of angina attacks as well as intakes of tablets of nitroglycerin for the above attacks to be arrested; besides, it lowers systolic and diastolic arterial pressure, enhances exercise tolerance, increase rate of circular shortening of left ventricular myocardium fibres, decreases total peripheral vascular resistance. In conclusion, apart from antihypertensive and positive inotropic action Capoten has a coranolytic effect.

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The article deals with electro-kinetic potential of cellular nucleus considered as an indicator of unspecific reactivity and presents some data on molecular and cellular mechanisms of adreno- and muscarino-receptive interactions, such as adrenalin, noradrenaline and DOPA blood levels, lipid peroxidation, erythrocyte resistance to peroxidation. The attempt is made to comprehend directions and trends of aforementioned processes in patients with stable and unstable stenocardia as well as in myocardial infarction with regard to sex and influence of central M-cholinoblockader amizyl. The drug provides adaptive effect, corrects affected adreno-reception, protects biomembranes from lesion, promotes their "fluidity" and reduces rigidity.

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