Publications by authors named "A Shchegolev"
The study aimed to analyze the literature data on postmortem changes in the brain and their use to determine the time since death. The earliest manifestations of brain cell autolysis are detected by electron microscopy (15-20 minutes after death). The longer the postmortem period, the more morphofunctional changes in the brain are revealed by histological, histochemical, and immunohistochemical studies.
View Article and Find Full Text PDFUnlabelled: is to assess the effectiveness of a new neuroanesthetic protocol for treating degenerative lumbar spine diseases in high-risk patients.
Materials And Methods: Two groups of patients with a high risk of anesthesia and surgery determined by the authors' clinical decision support system (CDSS) have been prospectively studied. A new neuroanesthetic protocol was used in the experimental group (EG, n=25), while the control group (CG, n=25) underwent intravenous anesthesia based on propofol and fentanyl.
Article Synopsis
- - The study investigates changes in astrocytes related to brain diseases by analyzing GFAP (glial fibrillary acidic protein) expression in brain tissue from deceased newborns, examining samples based on varying postmortem periods.
- - Tissue samples from 48 deceased newborns were categorized into 8 groups, and immunohistochemical analysis showed a decrease in GFAP+ staining areas, indicating a reduction in fibrotic astrocytes over time.
- - The findings highlight that postmortem changes in GFAP expression must be considered in tissue sampling for research and forensic diagnosis, as they can affect the differentiation from lifetime brain lesions.
: This study analyzes the issues of position dislocation of the head of the superior poles and lateral points of the outer edge of the middle divisions of each of the thyroid lobes (TL) changes. The purpose was to provide an intravital position study of the clinical anatomy of the middle and superior poles of the thyroid gland (TG). : We used data on anthropometry obtained during the study and data from MRI of the neck organs and anatomical formations of 100 healthy individuals, comprising 55 (55%) female and 45 (45%) male participants.
View Article and Find Full Text PDFThe morphometric characteristics of brain tissue were studied based on autopsy material from 49 deceased newborns divided into 7 groups based on the time after death. Samples were taken from the upper (frontal lobe) and lower (occipital lobe) regions relative to the supine position of the body. Paraffin sections were prepared from these samples and stained with hematoxylin and eosin.
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