A comparative study of multiple neural network for detection of COVID-19 on chest X-ray.

Coronavirus disease of 2019 or COVID-19 is a rapidly spreading viral infection that has affected millions all over the world. With its rapid spread and increasing numbers, it is becoming overwhelming for the healthcare workers to rapidly diagnose the condition and contain it from spreading. Hence it has become a necessity to automate the diagnostic procedure.

Isoniazid preventive treatment in children in two districts of South India: does practice follow policy?

Setting: Two districts of Tamil Nadu, India

Objectives: To determine the proportion of household contacts aged <6 years of patients with tuberculosis (TB) with positive sputum microscopy results who initiated and completed isoniazid preventive treatment (IPT), and to determine reasons for non-initiation and non-completion of IPT.

Design: Household visits were conducted on a random sample of adult patients registered during January-June 2012 to identify household contacts aged <6 years.

Results: Among 271 children living with 691 index patients, 218 (80%) were evaluated and 9 (4%) were diagnosed with TB.

Genetic variation of polymorphic NOS STR locus in ten Indian population groups.

The genotyping of 313 random individuals belonging to ten different population groups from three different states of India was performed for polymorphic pentanucleotide repeat present in the 5'-flanking region of nitric oxide synthase gene (NOS2A) to study the effect of geographical and linguistic affiliations on the genetic affinities among these groups. Likelihood ratio tests showed that all the ten populations for this locus were in Hardy Weinberg equilibrium. Eleven different alleles ranging from 7 repeat to 17 repeats and 46 different genotypes were observed.

Characterization of TPMT minisatellite locus in five ethnic groups of India.

A total of 206 random, healthy individuals belonging to five distinct ethnic groups (Ezhavas, Arayas, Nairs, Vishwakarmas and Muslims) were analyzed for 18 bp VNTR repeat polymorphism present in the 5'flanking region of theThiopurine Methyl Transferase gene (TPMT). In the present study, the population data of TPMT minisatellite was compared with the population data of other loci and the utility of minisatellite was evaluated in population studies. Human tandem repeat alleles of the TPMT minisatellite locus were characterized for the length polymorphism.

Synthesis and bioassay of a new class of heterocycles pyrrolyl oxadiazoles/thiadiazoles/triazoles.

A new class of heterocycles pyrrolyl thiadiazoles, pyrrolyl oxadiazoles and pyrrolyl triazoles were prepared from arylsulfonylethenesulfonylacetic acid methyl ester and tested for their antimicrobial and cytotoxic activities.