Supplemental systemic oxygen support using an intestinal intraluminal membrane oxygenator.

An intraluminal membrane oxygenator (IMO) prototype was surgically inserted in the ileum and evaluated as a method of supporting systemic oxygenation in an acutely hypoxemic porcine model. Animals were assigned randomly to the test (n = 12) or the control (n = 8) groups, which underwent identical protocols with the exception of the O2 flow in the IMO device, which was shut off in the control group. In each case, hypoxia was induced by a reduction in the inspired oxygen fraction (FiO2) to 0.

Gastric tonometry in healthy volunteers: effect of ranitidine on calculated intramural pH.

Objective: To determine if intraluminal production of CO2 leads to underestimation of gastric intramural pH (pHi) by tonometry.

Design: Nonrandomized controlled study.

Patients: Healthy volunteers.

Efficacy of large-bore intravenous fluid administration sets designed for rapid volume resuscitation.

We tested the hypothesis that large-bore iv tubing sets provide greater in vitro flow rates than conventional sets currently utilized for the administration of normal saline. The study was conducted in two parts. First, flow rates were measured using a conventional iv tubing set under gravity and 300 mm Hg of pressure, and four large-bore iv tubing sets under gravity.

Evaluation of the Datascope ACCUSAT pulse oximeter in healthy adults.

Arterial hemoglobin oxygen saturation measured with the Datascope ACCUSAT pulse oximeter was compared with simultaneous arterial hemoglobin oxygen saturation measurements in healthy adult volunteers. One hundred thirty-five arterial blood samples ranging in saturation from 63 to 100% were obtained from 15 adults, aged 20 to 43 years. These subjects had different skin pigmentation, hematocrit, and smoking habits.

Simultaneous comparison of three noninvasive oximeters in healthy volunteers.

Noninvasive monitoring of arterial hemoglobin oxygen saturation (SaO2) from the Nellcor N-100 and the Ohmeda-Biox 3700 pulse oximeters were compared with SaO2 measured simultaneously by the Hewlett-Packard 47201A ear oximeter. A total of 868 pairs of data points ranging in saturation from 55-100% were obtained from 31 healthy adult volunteers of different ages, sex, skin pigmentation, height, weight, hematocrit, and smoking habits. Steady state and rapidly changing hypoxic conditions were achieved by varying the inspired O2 concentration between 10 and 100%.