Astrocytes in Spinal Cord Injury: Current Opportunities and Prospects for Directional Polarization.

Activation of astrocytes during spinal cord injury (SCI) is accompanied by changes in their morphology and functional activity, possibly having severity-, localization-, and time-dependent features. The understanding of the role of reactive astrocytes has undergone significant changes over the last decades, and new data are still emerging to assess the diversity of functional manifestations of reactive cells. This review discusses the current understanding of astrocyte behavior, possible manifestations of their negative and positive roles in SCI, and the prospects for using various methods of directed polarization of astrocytes to improve post-traumatic outcomes.

Neutralizing Antibodies in COVID-19 Serum from Tatarstan, Russia.

The severity of COVID-19 is a result of the complex interplay between various branches of the immune system. However, our understanding of the role of neutralizing antibodies and the activation of cellular immune response in COVID-19 pathogenesis remains limited. In this study, we investigated neutralizing antibodies in patients with mild, moderate, and severe COVID-19, analyzing their cross-reactivity with the Wuhan and Omicron variants.

[The clinical and hemostasiological features of chronic hepatitides of different genesis].

Aim: To comparatively characterize clinical, biochemical, and hemostasiological parameters in patients with chronic alcoholic hepatitis (CAH) and chronic mixed hepatitis (CMH), i.e. CAH + chronic hepatitis C.

[The necessity of taking into account sanogenetic and pathogenetic reactions in the treatment of patients with the neurodystrophic form of lumboischialgia].

The authors have analyzed the results of clinico-instrumental examination of patients with a neurodystrophic form of lumbar ischialgia associated with lumbar osteochondrosis and specified two groups of symptoms: (1) due to pathogenetic manifestations of the disease and (2) due to sanogenetic reactions of the body.