Publications by authors named "A Seto"

Vascular access for coronary, peripheral, and structural interventions has changed significantly over the past two decades. The evolving demand for both large-bore access for valvular interventions and mechanical support devices, and for safer access for coronary interventions, in patients with comorbidities have driven progress in these areas. This review will provide an overview of the techniques of arterial access in the femoral, forearm (radial and ulnar), and alternative (transcarotid, transaxillary, and transcaval) locations based on the latest evidence and experience.

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  • The study investigated cardiac sympathetic nerve function in patients with severe aortic stenosis (AS) using MIBG imaging before and after transcatheter aortic valve implantation (TAVI).
  • Out of 26 patients, preoperative measures of cardiac function showed significant correlations with clinical markers, but postoperative nerve function did not improve significantly, even though BNP levels decreased after TAVI.
  • Five patients experienced notable recovery in cardiac function, indicating thinner left ventricular wall thickness and a reduction in mortality risk over a 5-year prediction model.
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Several novel software systems have been developed for the reconstruction of the coronary artery tree and the calculation of fractional flow reserve (FFR) from coronary artery angiography images without coronary artery instrumentation: FFR, Computational pressure-flow dynamics derived FFR, quantitative flow ratio (QFR), and vessel FFR. In this report, we review the current evidence on each software, their contemporary use, and future directions.

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Objective: This study aimed to evaluate the diagnostic performance of 99m Tc-hydroxymethylene diphosphonate ( 99m Tc-HMDP) imaging for cardiac amyloidosis and to demonstrate changes in cardiac uptake of 99m Tc-HMDP after tafamidis treatment.

Methods: Seventy-five patients with suspected cardiac amyloidosis who underwent 99m Tc-HMDP imaging were included. We compared visual Perugini grades and semiquantitative heart-to-contralateral (H/CL) area ratios, myocardial maximum standardized uptake value (SUVmax), and peak of SUV (SUVpeak) between cardiac transthyretin amyloidosis (ATTR) and amyloid light-chain amyloidosis (AL).

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  • The study investigated the left atrial septal pouch (LASP), a variant found in about one-third of hearts due to incomplete fusion of two septal structures, the septum primum (SP) and septum secundum (SS).
  • Out of 864 heart scans analyzed, 242 patients (31.4%) were found to have LASP, while 181 (23.5%) had a patent foramen ovale (PFO) and 339 (44.0%) had a completely fused septum (CFS).
  • Significant differences were noted in the lengths of the SS and overlapping SP among different groups, with LASP hearts showing longer measurements, but similar atr
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