Publications by authors named "A Seshadri Ramakrishnan"
Introduction: Hypogonadism is a common comorbidity associated with several metabolic disorders including type 2 diabetes (T2D) that can remain undetected without proper screening. Here, we evaluated the prevalence of hypogonadism in Indian male patients with T2D with or without obesity.
Methods: In this prospective, observational study, male patients with T2D and hypogonadism were evaluated symptomatically using the androgen deficiency in ageing male (ADAM) questionnaire at baseline and confirmed on the basis of total testosterone (TT) levels (<300 ng/dL) at Days 5-7 (Visit 2) and 9-14 (Visit 4) assessed after 12 hours of fasting between 8 AM and 10 AM.
Health Disparities and Hormone Therapy Prescribing for Early, Peri-, and Postmenopausal Women: A Scoping Review.
J Racial Ethn Health Disparities
December 2024
Article Synopsis
- - This study explored whether there are health disparities in the prescription and use of menopause hormone therapy among perimenopausal and early postmenopausal women in the USA, by reviewing observational studies from 1940 until October 2023.
- - Researchers found 16 different health disparities related to hormone therapy, noting significant differences based on ethnicity, education, medical conditions, and practitioner specialization.
- - The findings indicate long-standing disparities in hormone therapy access and usage, highlighting the need for improved education for healthcare providers to better serve underserved populations.
The study reported herein attempts to understand the neural mechanisms engaged in the conscious control of breathing and breath-hold. The variations in the electroencephalogram (EEG) based functional connectivity (FC) of the human brain have been investigated during attentive breathing at 2 cycles per minute (cpm). The study presents its novelty through three main aspects.
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- Patients with head and neck tumors undergoing free flap reconstructions are at high risk of postoperative venous thromboembolism (VTE), prompting a review of anticoagulation practices and the use of subcutaneous heparin in this study.
- A systematic review included 15 studies, revealing VTE rates between 0% and 9.6%, while a six-year analysis at the institution showed a low VTE rate of 0.76% among 393 patients receiving heparin.
- The study concluded that administering 5000 units of subcutaneous heparin every 8 hours is effective in minimizing VTE and maintaining a comparable rate of surgical site hematoma, suggesting its routine use may be beneficial.
Article Synopsis
- The study investigates the prevalence of diabetic macular edema (DME) in type 2 diabetic patients with and without diabetic nephropathy (DN) by using optical coherence tomography (OCT).
- Conducted over a year at Saveetha Medical College, the study included 120 patients—60 without nephropathy and 60 with nephropathy—assessing various health metrics, including blood sugar levels and kidney function.
- Results indicated that a significantly higher percentage of patients in the nephropathy group had both a longer duration of diabetes and poorer HbA1c levels, with only 1.7% of patients without nephropathy developing DME compared to higher rates in the nephropathy group.