Immunocompromised children are at risk of developing severe COVID-19 infection. We conducted a pilot prospective study to evaluate the impact of cancer treatment and stem cell transplantation on immunogenicity of two doses of BNT162b2 vaccine in pediatric patients. Humoral, B- and T-cell responses to the BNT162b2 vaccine were assessed before, after the first and the second dose in patients aged 5-12 years (n = 35) and in a group of healthy donors (HD, n = 12).
View Article and Find Full Text PDFBackground: This study evaluated the safety and efficacy of BioMime sirolimus-eluting stent (SES) system, with an ultra-low strut thickness (65 µm), in real-world all-comers population with coronary artery stenosis (CAD).
Methods: This was a post-marketing, multicenter, single-arm, observational clinical registry among patients undergoing intervention for CAD. Patients were clinically followed up at 1, 9, 12, and 24 months after the index percutaneous coronary intervention.
Improving the synchrony between amino acids (AAs) and glucose appearance in the blood can support the growth performance of weaned pigs fed a low crude protein (CP) diet. This can be achieved using a diet with a low amylose-to-amylopectin ratio (AM/AP). The aim of this experiment was to evaluate whether reducing the AM/AP by using a corn variety characterized by a high amylopectin content, in the weaning diet can sustain growth performance and improve the intestinal health of pigs fed a low-CP diet.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
December 2024