Publications by authors named "A Serizawa"
Background: Postoperative pancreatic fistula (POPF) is one of the potentially serious complications after gastrectomy for gastric cancer (GC). Drain amylase level is a predictor of POPF in open and laparoscopic gastrectomy, but no study has focused on minimally invasive surgery (MIS), including robotic gastrectomy (RG). This study assesses the effect of drain amylase levels for POPF in MIS and develop a prediction model in the MIS era.
View Article and Find Full Text PDFBackground: Advanced gastric cancer with gastric outlet obstruction (GOO) causes malnutrition and medication adherence issues, leading to a poor prognosis. We developed a novel multimodal, less invasive treatment approach for gastric cancer patients with symptomatic GOO: laparoscopic stomach-partitioning gastrojejunostomy (LSPGJ) combined with neoadjuvant chemotherapy (NAC), followed by minimally invasive gastrectomy with reuse of gastrojejunostomy. This study is a retrospective analysis of the safety and feasibility of our treatment strategy.
View Article and Find Full Text PDFArticle Synopsis
- - This study focused on 111 patients with advanced gastric cancer who were treated with nivolumab to monitor their disease progression and evaluate treatment response using serum inflammatory markers like CRP-to-albumin ratio (CAR), platelet-to-lymphocyte ratio (PLR), and neutrophil-to-lymphocyte ratio (NLR).
- - Results indicated an overall response rate of 11.7% and a disease control rate of 44.1%, with median overall survival of 14 months and progression-free survival of 4.1 months.
- - Changes in the inflammatory markers after therapy proved to be useful in predicting treatment response, with specific cutoff values identified for CAR, PLR, and NLR that correlated
Article Synopsis
- - The study assessed the effectiveness of laparoscopic gastrectomy (LG) performed by non-ESSQS-qualified surgeons when guided by ESSQS-qualified surgeons in patients with stage ≤ III gastric cancer.
- - A total of 1,030 patients were analyzed, with results showing that the 3-year recurrence-free survival rate was slightly higher for non-ESSQS surgeons (84.4%) compared to their ESSQS counterparts (81.7%), indicating non-inferior outcomes.
- - Overall, both patient groups had similar 5-year recurrence-free survival rates and overall survival rates, suggesting that non-ESSQS-qualified surgeons can achieve comparable oncological results in a high-volume center when receiving intraoperative guidance.
Article Synopsis
- A study evaluated the effectiveness of improved surgical procedures for preventing late complications in patients undergoing minimally invasive total gastrectomy for gastric cancer, comparing two groups over ten years.
- The researchers found that the rate of late overall complications and intestinal complications significantly decreased after standardizing the surgical procedure, indicating better outcomes for patients.
- Specifically, the incidence of late complications fell from 9.0% in the first group (before standardization) to 2.9% in the second group (after standardization), highlighting Period-I as a risk factor for these complications.