Chemical characterisation, hypoglycaemic and renoprotective effects of aqueous leaf extract of on fructose-induced metabolic syndrome in rats.

In the present study, we chemically characterised the aqueous leaf extract of by HPLC-TOF/MS and evaluated its effects on fructose-induced metabolic syndrome (MetS) in Wistar rats. MetS groups were given (10% w/v) fructose solution to drink for 9 weeks, whereas, normal animals received ordinary water. LG extract was administrated to treated groups by gavage for the last 6 weeks of the experimental period.

aqueous extract improves insulin sensitivity and hepatic steatosis in rodent model of fructose-induced metabolic syndrome.

Context: Fructose consumption is associated with the development of obesity and metabolic syndrome (MetS) in human and animal models.

Objective: This study investigates the ability of an aqueous extract of Asso (AH) to ameliorate fructose-induced MetS in Male Wistar rats.

Methods: AH extract at doses of 100, 200 and 400 mg/kg b.

Epigenetic modifiers 5-aza-2'-deoxycytidine and valproic acid differentially change viability, DNA damage and gene expression in metastatic and non-metastatic colon cancer cell lines.

DNA methylation and histone modifications are major components of cellular epigenetic pattern determining gene expression. Cancer cells have their own epigenetic array, which can be different in cells of primary and metastatic tumors. In the present work we investigated effects of 1 mM valproic acid (VPA), a histone deacetylase inhibitor and 0.

Protective activity of Hertia cheirifolia extracts against DNA damage, lipid peroxidation and protein oxidation.

Context: Hertia cheirifolia L. (Asteraceae), a perennial shrub widely distributed in Northern Africa, is traditionally used to treat inflammatory disorders.

Objective: The protective effect of methanol (Met E) and aqueous (Aq E) extracts of Hertia cheirifolia against DNA, lipid and protein oxidation was investigated.

Phytochemical screening and anti-inflammatory properties of Algerian Hertia cheirifolia methanol extract.

Context: Hertia cheirifolia L. (Asteraceae) is traditionally used in Northern Africa to treat various inflammatory infections. However, few studies on this plant have been reported.