Publications by authors named "A Semprini"
Background: A noninvasive ventilation (NIV) mask has been designed to deliver NIV with expiratory washout to improve efficacy of ventilation by optimizing clearance of expired gases from the anatomic dead space. This study compared the performance and comfort of a novel investigational mask with expiratory washout with a conventional mask during NIV therapy.
Methods: In this pilot crossover study, participants with severe stable COPD attended a single visit to receive bi-level NIV through 2 masks; the investigational mask with expiratory washout and a conventional mask.
Background: Closed-loop oxygen control systems automatically adjust the fraction of inspired oxygen (FiO) to maintain oxygen saturation (SpO) within a predetermined target range. Their performance with low and high-flow oxygen therapies, but not with non-invasive ventilation, has been established. We compared the effect of automated oxygen on achieving and maintaining a target SpO range with nasal high flow (NHF), bilevel positive airway pressure (bilevel) and continuous positive airway pressure (CPAP), in stable hypoxaemic patients with chronic cardiorespiratory disease.
View Article and Find Full Text PDFIntroduction This study presents an innovative model of integrated dermatology service delivery. Kauri HealthCare (KHC) is a general practice serving around 19 000 patients in Palmerston North, New Zealand. A 'mini clinic' is provided by an on-site dermatologist that is available for patients of KHC.
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- Eczema is a common skin condition typically treated with emollients and topical corticosteroids, but there is a growing interest in botanical therapies despite limited clinical evidence.
- A randomized controlled trial (RCT) is being conducted to test the safety and effectiveness of a mānuka oil-based emollient cream (2% ECMT-154) for moderate to severe eczema, involving 118 participants in New Zealand who will apply the cream for six weeks.
- The study's results will evaluate symptom improvement and treatment acceptability, with findings shared through publications and presentations if the therapy proves effective.
Social media platforms are used for support and as resources by people from the endometriosis community who are seeking advice about diagnosis, education, and disease management. However, little is known about the scientific accuracy of information circulated on Instagram about the disease. To fill this gap, this study analysed the evidence-based nature of content on Instagram about endometriosis.
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