Publications by authors named "A Schmermund"

Purpose Of Review: Cardiac computed tomography (CT) is an established non-invasive imaging tool for the assessment of coronary artery disease. Furthermore, it plays a key role in the preinterventional work-up of patients presenting with structural heart disease.

Recent Findings: CT is the gold standard for preprocedural annular assessment, device sizing, risk determination of annular injury, coronary occlusion or left ventricular outflow tract obstruction, calcification visualization and quantification of the target structure, and prediction of a co-planar fluoroscopic angulation for transcatheter interventions in patients with structural heart disease.

View Article and Find Full Text PDF

Background: Pericoronary adipose tissue attenuation (PCAT) is a marker of inflammation of the pericoronary fat tissue, which can be assessed by coronary computed tomography angiography (CCTA). Its prognostic value was reported in previous studies. Nevertheless, the relationship between PCAT, plaque burden and coronary artery disease (CAD) severity, are not well defined.

View Article and Find Full Text PDF

Background: Statin therapy promotes the progression of coronary artery calcification (CAC). Comparing patients on high (HIST) vs. low-to-intermediate intensity statin therapy (LIST), randomized controlled trials with a one-year follow-up failed to document a relevant difference in the Agatston score and CAC volume.

View Article and Find Full Text PDF
Article Synopsis
  • The Heinz Nixdorf Recall Study aimed to determine how well computed tomography (CT) predicts cardiovascular events compared to just using traditional risk factors.
  • During the study (2000-2003), 4,355 individuals aged 45-75 with no heart disease were evaluated using the Atherosclerotic Cardiovascular Disease (ASCVD) score and underwent cardiac CT to assess coronary artery calcification (CAC).
  • Results showed that combining the ASCVD score with CAC grading improved risk classification significantly, with higher CAC scores correlating with more events like heart attacks and strokes over 20 years, suggesting that CT assessments should be used more in primary prevention.
View Article and Find Full Text PDF

The interventional treatment of high-risk patients remains challenging and has a high potential for improvement despite all technical innovations. Mechanical circulatory support (MCS) systems can be meaningful depending on the clinical situation, although a clear study situation for this is so far lacking. Multivessel coronary disease and a high SYNTAX score combined with impaired ventricular function is a possible predictor combination for the use of MCS that justifies the higher risk of complications.

View Article and Find Full Text PDF