Effectiveness of a Mindfulness-Based Mobile Application for the Treatment of Depression in Ambulatory Care: Protocol for a Randomized Controlled Trial.

Background: Patients with major depressive disorder (MDD) often experience relapses despite regular treatment with pharmacotherapy and psychotherapy. Further, long waiting lists and more demand than treatment capacity characterize ambulatory settings. Mindfulness-based interventions proved to be effective in relapse prevention in MDD.

[70 plus: a Challenge for the Family Doctor and the Gastroenterologist].

In elderly patients, dysphagia, fecal incontinence, gastrointestinal malignant diseases and bleeding as well as ischemia of the small and large bowel are increased compared to younger patients. These diseases often significantly decrease the quality of life and survival, however, they can often be treated quite successfully if the diagnosis is made early enough. History and clinical presentation in the elderly are often unspecific, thus further investigations – especially in the emergency situation – such as laboratory examinations, abdominal ultrasound, computer tomography and endoscopy are often necessary.

Changing incidence of gastric and oesophageal cancer subtypes in central Switzerland between 1982 and 2007.

Several Western countries have reported a decrease in the incidence of noncardia gastric adenocarcinoma and a strong increase in the incidence of oesophageal and cardia adenocarcinoma. We examined incidence rates of gastric and oesophageal cancer by subsite and histology in Central Switzerland over the last 26 years. Data on biopsy-diagnosed gastric and oesophageal carcinoma incidence during 1982-2007 were obtained from the Cancer Registry of the Institute of Pathology, Lucerne, the Medical Centre for Central Switzerland.

[Autoimmune pancreatitis: new concepts of an often overlooked disease].

Autoimmune pancreatitis is characterized by a lympho-plasmacytic infiltrate centred around the pancreatic ducts along with venulitis; it can produce a mass-like fibroinflammatory lesion and often simulates pancreatic malignancy or chronic pancreatitis of other types. This may lead to unnecessary surgical interventions. Patients, who are usually over 40 years of age, show 1) mild unspecific abdominal pain, 2) increased serum immunoglobulins (specifically IgG4) and autoantibodies, and 3) diffuse or focal enlargement of the pancreas with pancreatic strictures and sometimes jaundice due to biliary obstruction (detectable by US, CT, MRI, ERCP and/or endoscopic ultrasound (EUS)).