Publications by authors named "A Schlegtendal"
Purpose: Lack of a control group(s) and selection bias were the main criticisms of previous studies investigating the prevalence of post-coronavirus disease 2019 (COVID-19) syndrome (PCS). There are insufficient data regarding paediatric PCS, particularly in the SARS-CoV-2 Omicron era. As such, our study investigated PCS-associated symptoms in a representative control-matched cohort.
View Article and Find Full Text PDFUnlabelled: In 2022, over 1,000,000 people from Ukraine fled to Germany, mostly women and children. The aim of this study was to determine health status and socio-demographic background of Ukrainian refugee minors in Germany and to compare that to German minors. In this study, Ukrainian refugees of all ages, who voluntarily made contact with the study centres via flyers or refugee shelters, were interviewed with the help of trained interpreters from 09-12/2022.
View Article and Find Full Text PDFBackground: Little is known about specific safety aspects in children with significant comorbidities receiving the mRNA vaccine BNT162b2, as approval studies did not address this population. This study's purpose is to evaluate safety and adverse events in these children compared to healthy children.
Methods: In this prospective, multicentre, industry-independent cohort study, caregivers whose children received BNT162b2 were asked to participate in an online questionnaire.
Article Synopsis
- * Data were collected from 408 PCD patients across 12 countries, focusing on their lung function and the presence of common respiratory pathogens, with a significant finding that those with certain pathogens had lower lung function scores.
- * The results indicated that certain pathogens were strongly associated with decreased lung function, particularly in adults, highlighting the need for early eradication strategies and timely treatment of infections in PCD patients.
Article Synopsis
- - Primary ciliary dyskinesia (PCD) is a rare genetic disorder affecting cilia function, impacting respiratory health, with no cure available; supportive therapies like physical activity are recommended despite a lack of scientific backing.
- - A multi-center randomized controlled trial will involve 158 participants to test whether a personalized physical activity program improves quality of life (QoL) compared to standard recommendations over six months, utilizing activity trackers and regular assessments.
- - The trial aims to address challenges posed by the diversity of PCD cases and age variation through stratified randomization, emphasizing individualized approaches and maintaining close contact with trainers to enhance outcomes.