Publications by authors named "A Schindler"

Objective: To propose a European consensus for managing and treating laryngopharyngeal reflux disease (LPRD) to guide primary care and specialist physicians.

Methods: Twenty-three European experts (otolaryngologists, gastroenterologists, surgeons) participated in a modified Delphi process to revise 38 statements about the definition, clinical management, and treatment of LPRD. Three voting rounds were conducted on a 5-point scale and a consensus was defined a priori as agreement by 80% of the experts.

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Purpose: In the treatment of hepatocellular carcinoma (HCC) with transarterial radioembolization (TARE), identifying reliable biomarkers for predicting survival outcomes remains a critical challenge. We aimed to address this gap by investigating the significance of serum cytokines associated with inflammation as potential biomarkers for the selection of patients for TARE.

Methods: Our retrospective study involved 161 patients diagnosed with HCC who underwent Y90 radioembolization at our medical center between 2010 and 2020.

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Objective: Veterans with a history of blast-related mild traumatic brain injury (mTBI) and posttraumatic stress disorder (PTSD) may be at risk for greater cognitive concerns and worse functional outcomes compared to those with either condition in isolation. However, traditional neuropsychological assessment approaches have yielded equivocal results in these populations. The present study examined an alternative method for detecting subtle cognitive inefficiencies: neurocognitive intraindividual variability (IIV), a measure of within-person performance consistency.

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Article Synopsis
  • The study explores the daily challenges and resources that individuals with chronic oropharyngeal dysphagia (OD) face, highlighting its importance in person-centered care, which is often overlooked in research.
  • In-depth interviews with 25 Italian adults suffering from OD due to cancer or neurodegenerative diseases revealed that challenges span physical, practical, and social areas, with many participants describing difficulties in care and healthcare access.
  • Participants utilized various coping strategies and leaned on personal strengths and support systems, with many reporting significant changes in their life perspectives due to their condition; the study emphasizes the need for future research to enhance tailored care and inform healthcare policies.
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Article Synopsis
  • - The study investigates the use of Fiberoptic Endoscopic Evaluation of Swallowing (FEES) in children with Spinal Muscular Atrophy Type 1 (SMA1), analyzing its feasibility and effectiveness compared to VideoFluoroscopic Swallow Study (VFSS).
  • - Results show FEES was safely performed on all participants, revealing issues with swallowing efficacy and safety in nearly all children, and highlighting that most exhibited a specific dysphagia phenotype.
  • - The findings indicate a strong agreement between FEES and VFSS results, confirming that dysphagia in SMA1 patients often involves significant residue in the piriform sinuses.
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