Genetics Adviser: The development and usability testing of a new patient digital health application to support clinical genomic testing.

Purpose: Increasing demand for genomic testing coupled with genetics workforce shortages has placed unsustainable pressure on standard models of care. Digital tools can offer improved access, efficiency, and cost savings. We created a patient-facing digital health application to support genomic testing.

Chemical Resistance of Modified Wood Veneers in Sustainable Load Bearing Elements.

In the pursuit of sustainable engineering solutions, material selection is increasingly directed toward resources that offer functional efficacy, economic feasibility, and minimal environmental impact. To replace environmentally damaging materials like aluminum with more sustainable alternatives like wood-based materials, it is essential to improve the durability and longevity of wood. This study explores the potential suitability of modified veneers as an outer protective layer for unmodified wooden load-bearing elements, providing a cost-effective and resource-efficient alternative to bulk modification.

A conditional multi-label model to improve prediction of a rare outcome: An illustration predicting autism diagnosis.

Objective: This study aimed to develop a novel approach using routinely collected electronic health records (EHRs) data to improve the prediction of a rare event. We illustrated this using an example of improving early prediction of an autism diagnosis, given its low prevalence, by leveraging correlations between autism and other neurodevelopmental conditions (NDCs).

Methods: To achieve this, we introduced a conditional multi-label model by merging conditional learning and multi-label methodologies.

Fusion of cellulose microspheres with pulp fibers: Creating an unconventional type of paper.

Cellulose microspheres (CMS) are a type of spherical regenerated cellulose particles with versatile properties which have been used as carrier materials in medical and technical applications. The integration of CMS into paper products opens up novel application scenarios for paper products in a wide range of fields. However, the incorporation of CMS carriers into paper products is challenging and hitherto no reports do exist in literature.

The effects of telerehabilitation in adults with complex biventricular congenital heart conditions: protocol for a multi-centre, randomised controlled trial-CH-FIT.

Background: Accumulated evidence suggests that exercise training exerts beneficial effects on people with congenital heart conditions. These findings are predominantly derived from small, single-centre exercise trials conducted in outpatient rehabilitation facilities. In recent years, the delivery of exercise interventions remotely has increased through digital communications technology (telerehabilitation).