Publications by authors named "A Scarabello"
Background: Epilepsy, characterized as a network disorder, involves widely distributed areas following seizure propagation from a limited onset zone. Accurate delineation of the epileptogenic zone (EZ) is crucial for successful surgery in drug-resistant focal epilepsy. While visual analysis of scalp electroencephalogram (EEG) primarily elucidates seizure spreading patterns, we employed brain connectivity techniques and graph theory principles during the pre-ictal to ictal transition to define the epileptogenic network.
View Article and Find Full Text PDFBackground: Human papillomavirus (HPV) infection is linked to several cancers, including anal and oral cancers. The incidence of anal cancer is particularly high among HIV-positive men who have sex with men (MSM). DNA methylation markers have shown promise as biomarkers for identifying precancerous lesions and cancer in HPV-infected individuals.
View Article and Find Full Text PDFArticle Synopsis
- Bullous pemphigoid (BP) is a rare autoimmune skin disorder, becoming more frequent with associations noted with certain diabetes medications called gliptins.
- A study analyzed 30 idiopathic bullous pemphigoid (IBP) patients and 86 gliptin-associated BP (GABP) patients to explore genetic risk factors.
- The research found a significant link between the HLA-DQB1*03:01 allele and both IBP and GABP, suggesting genetic markers that could indicate susceptibility to BP, particularly in individuals who have taken gliptins.
Article Synopsis
- - This study examined ictal bradycardia (IB) and asystole (IA) in patients with sleep-related hypermotor epilepsy (SHE) using video-EEG recordings.
- - Researchers analyzed data from 200 patients, finding that IB/IA occurred in 2% of them, with IA averaging 10 seconds and one case of IB noted.
- - The patients with IB/IA were more likely to have focal cortical dysplasia (FCD) and pathogenic variants in specific genes related to the mTOR pathway compared to those without these conditions.
Article Synopsis
- Cutaneous pseudolymphomas are a diverse group of skin diseases that look like cutaneous lymphoma but have different causes and symptoms, and they may appear without any known trigger or following factors like medications, tattoos, or infections.
- These conditions can present in various ways, from single lesions to widespread issues, with some cases lasting from weeks to years and potentially recurring after disappearing on their own or after treatment.
- The case study discussed involves a man with a single nodule that was identified as resembling a primary cutaneous CD30+ T-cell lymphoproliferative disorder, highlighting the complex nature of diagnosing these skin diseases.