Silybum marianum Extract: A Highly Effective Natural Alternative to Retinoids to Prevent Skin Aging Without Side Effects.

Background: Vitamin A, or retinol, is one of the most effective antiaging molecules, but it presents issues with photo-sensitivity and irritation. Alternatives are emerging, but have so far been less effective.

Objective: Here, we present a Silibum marianum extract (SME) as a retinol-like ingredient providing both safety and efficacy.

Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota.

(1) Background: Ultraviolet radiation takes part in photoaging and pigmentation disorders on skin. Epigallocatechin gallate (EGCG) is a well-known brightening and photoprotective compound but it faces limitations in terms of stability and solubility. (2) Methods: A more stable and water-soluble glucoside called EGCG-G1 was obtained by enzymatic glucosylation of EGCG.

Analysis of Active Components and Transcriptome of Callus Extract and Its Effects against Oxidative Stress and Wrinkles in Skin.

(FR), a perennial flower of the Iris family (Iridaceae), is widely used in cosmetics despite limited scientific evidence of its skin benefits and chemical composition, particularly of FR callus extract (FCE). This study identified biologically active compounds in FCE and assessed their skin benefits, focusing on anti-aging. FR calli were cultured, extracted with water at 40 °C, and analyzed using Centrifugal Partition Chromatography (CPC), Nuclear Magnetic Resonance (NMR), and HCA, revealing key compounds, namely nicotinamide and pyroglutamic acid.

Facial pore refining by targeting dermal and epidermal functions: Assessment across age and gender.

Background: Conspicuous facial pores are benign but represent a cosmetic concern for men and women. Recent works described dermal and epidermal impairments as clinical causes of enlarged pores. Morphological modifications of skin at the site of pores were associated with collagen density loss, possible alteration of extracellular matrix and abnormal differentiation of keratinocytes.

Evaluation of the hydrating benefits of a cationic hyaluronic acid: From biological evaluation to consumer home use trial.

Active ingredients are often assessed based on physiological measurements, but innovative technologies to measure skin sensations can provide a holistic volunteer assessment of the use of an ingredient. In this paper, the hydrating benefits of a cationic hyaluronic acid (HA) were evaluated alongside clinical biometrics and innovative cognitive measurements to determine how biological benefits correlated with volunteers' feelings and perceptions of hydration. The results demonstrated that cationic HA provides hydrating benefits at the clinical level due to its film-forming properties.