Publications by authors named "A Saud"
Liver cancer ranks as the sixth most prevalent form of cancer and stands as the fourth leading cause of cancer-related fatalities on a global scale. The two primary types of liver cancer are hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). While ICC originates from the bile ducts, HCC develops from hepatocytes, which are the primary functional cells of the liver.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate how treatment affects serum interferon-alpha levels in female patients with systemic lupus erythematosus (SLE).
- Conducted between January and April 2022 at Baghdad Teaching Hospital, the study involved three groups: treated patients (group A), untreated patients (group B), and healthy controls (group C), with disease severity assessed via a specific index.
- Results indicated that untreated patients had significantly higher levels of interferon-alpha compared to treated patients, particularly among younger individuals and those with a shorter disease duration, suggesting treatment plays a crucial role in lowering interferon-alpha levels.
Anatomy of a hotspot: Cisplatin hotspots in the tdk gene of Escherichia coli.
Environ Mol Mutagen
November 2024
We previously reported that certain sub-regions of the thyA gene of Escherichia coli are more mutable than others when many different mutagens and mutators are analyzed (Mashiach et al., Mutation Research Fundamental Molecular Mechansims of Mutagenesis, 821: 111702, 2021). In this study, we focus on a single mutagen, cisplatin and verify that mutations occur preferentially at specific 3 bp sequences, but only when they appear in certain subregions of the gene.
View Article and Find Full Text PDFThe review examined the potential of starch-based drug delivery systems for managing breast cancer efficiently. It covered the background of breast cancer and the significance of drug delivery systems in treatment enhancement. Starch, known for its versatile physicochemical properties, was explored as a promising biopolymer for drug delivery.
View Article and Find Full Text PDFBackground: Orthopedic traumatology, a vital component of orthopedic surgery, poses significant challenges in managing complications and necessitating revision surgeries. These challenges impact clinical outcomes, healthcare economics, and patient well-being.
Objective: This study aimed to provide insights that informed clinical decision-making and improved patient outcomes by thoroughly examining the range of complications encountered in orthopedic traumatology.