Rheocarna Effectively Treats Oral Medicinal Therapy-Resistant Cutaneous Symptoms and Renal Failure Induced by Cholesterol Crystal Embolism.

An 80-year-old man presented to our hospital with worsening renal function and ambulation difficulties due to lower extremity symptoms that included livedo reticularis, gangrene, cyanosis, and ulcers in his legs. The patient was diagnosed with a cholesterol crystal embolism. Treatment with prednisolone and rosuvastatin was initiated; however, no improvements were observed in the patient's cutaneous symptoms or renal function.

Optimal seasonal schedule for producing biogenic volatile organic compounds for tree defense.

The leaves of many trees emit biogenic volatile organic compounds (BVOCs) that protect them from various threats, including herbivory, pathogens, and heat stress. In a previous study, we analyzed the optimal seasonal schedule for producing isoprene, a highly volatile BVOC, in leaves to mitigate heat damage and maximize net carbon gain. In this paper, we investigate the seasonal production schedule of BVOCs stored in leaves, such as monoterpenes and sesquiterpenes, which decay slowly.

Elevated plasma progranulin levels in the acute phase are correlated with recovery of left ventricular function in the chronic phase in patients with acute myocardial infarction.

Background: Progranulin is a secreted glycoprotein that regulates inflammation and wound healing. However, plasma progranulin levels in the acute phase and their clinical significance in patients with acute myocardial infarction (AMI) remain to be elucidated.

Objective: We aimed to investigate the relationship between the increase in plasma progranulin levels in the acute phase and the recovery of left ventricular function in the chronic phase in AMI patients.

Somatic mutation rates scale with time not growth rate in long-lived tropical trees.

The rates of appearance of new mutations play a central role in evolution. However, mutational processes in natural environments and their relationship with growth rates are largely unknown, particular in tropical ecosystems with high biodiversity. Here, we examined the somatic mutation landscapes of two tropical trees, (slow-growing) and (fast-growing), in central Borneo, Indonesia.

Photoexcitation and One-Electron Reduction Processes of a CO Photoreduction Dyad Catalyst Having a Zinc(II) Porphyrin Photosensitizer.

We have explored the photophysical properties and one-electron reduction process in the dyad photocatalyst for CO photoreduction, , in which the catalyst of -[Re(1,10-phenanthoroline)(CO)Br] is directly connected with the photosensitizer of zinc(II) porphyrin (), using time-resolved infrared spectroscopy, transient absorption spectroscopy, and quantum chemical calculations. We revealed the following photophysical properties: (1) the intersystem crossing occurs with a time constant of ∼20 ps, which is much faster than that of a single unit, and (2) the charge density in the excited singlet and triplet states is mainly localized on , which means that the excited state is assignable to the π-π* transition in . The one-electron reduction by 1,3-dimethyl-2-phenyl-2,3-dihydro-1-benzo[]imidazole occurs via the triplet excited state with the time constant of ∼100 ns and directly from the ground state with the time constant of ∼3 μs.