Publications by authors named "A Saray"
: Vitamin B complexes are frequently used in clinical practice for peripheral nerve trauma. However, there is a lack of scientific data on their effectiveness. This study aims to investigate the impact of the vitamin B complex on nerve recovery in a rat model of peripheral nerve paralysis.
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- Hermansky-Pudlak Syndrome (HPS) is a rare genetic disorder with symptoms including oculocutaneous albinism, bleeding issues, and potential lung and bowel complications, linked to mutations in genes critical for cellular transport.
- The study specifically focuses on HPS-9, associated with a variant in the BLOC1S6 gene, highlighting a novel Copy Number Variation (CNV) found in an Iranian family, which contributes to the understanding of this subtype's genetic basis.
- Results from Whole Exome Sequencing revealed a significant deletion in the BLOC1S6 gene, confirming the absence of its expression in affected individuals, which has implications for patient healthcare and future treatment strategies.
Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), necessitates effective management strategies. This study aims to evaluate the real-world efficacy of vedolizumab, a newer biological therapy, in treating IBD in Bosnia and Herzegovina. A retrospective observational study was conducted across six medical centers, involving 139 IBD patients, 76 with UC and 63 with CD.
View Article and Find Full Text PDFRenal function in patients with chronic hepatitis B during antiviral therapy.
Med Glas (Zenica)
February 2024
Aim To analyse the impact of the length of antiviral therapy with tenofovir disoproxil fumarate (TDF) on the renal function in patients with chronic hepatitis B (CHB). Methods A cross-sectional study included 75 patients with CHB treated with tenofovir, who had a normal renal function at the beginning of the treatment. Renal function was determined based on glomerular filtration rate (eGFR) value using the Modification of Diet in Renal Disease formula (MDRD).
View Article and Find Full Text PDFObjective: The aim of our study was to determine the etiological factors, treatment and outcome of patients with non-variceal bleeding from upper gastrointestinal tract.
Materials And Methods: This study enrolled 200 patients admitted to Sarajevo University Clinical Center with signs and symptoms of upper gastrointestinal bleeding, from January 2019 to July 2020. All patients had undergone gastroscopy, confirming the cause of gastrointestinal bleeding.