Tissue tracking analysis and left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy.

Hypertrophic cardiomyopathy (HCM) is the most frequent inherited cardiomyopathy in adults and may be associated with limiting symptoms and adverse clinical evolution, especially in the obstructive forms. Cardiac magnetic resonance (CMR) is a key technique to accurately diagnose the condition and tissue tracking strain analysis, a promising new tool to better identify and understand its mechanisms. We sought to investigate the association of tissue tracking CMR deformation parameters with obstructive HCM forms.

Prehospital critical care drug-therapy and 30-day mortality in patients with acute respiratory disease.

Background: Prehospital medication is a reality, and the role of these therapies must be explored to assess their validity, especially for acute respiratory diseases, which are usually associated with increased morbidity. The aim of this study was to examine the association of prehospital medication use with mortality in patients with acute respiratory disease.

Methods: A prospective, multicenter, emergency medical service (EMS) delivery cohort study was carried out in adults with unselected respiratory diseases managed by EMS who were transferred to the emergency department.

What Lies Beyond Personality Traits? The Role of Intolerance of Uncertainty, Anxiety Sensitivity, and Metacognition.

Background: Although personality trait models have become consolidated as the hegemonic taxonomical models for describing personality and provide excellent capacity for predicting variables of psychological interest (i.e., mental disorders), there are still important gaps in our knowledge about why personality traits predict those variables.

Novel prehospital lactate cut-off estimation for mortality: a multicentre observational study.

Objectives: Point-of-care testing available in prehospital settings requires the establishment of new medical decision points. The aim of the present work was to determine the cut-off of the lactate threshold that activates alert triggers for all-cause 2-day mortality.

Design: Multicentre, prospective, ambulance-based, observational study.

National early warning score 2 plus non-invasive capnography and perfusion index to estimate poor outcomes in emergency departments.

Background: The study of the inclusion of new variables in already existing early warning scores is a growing field. The aim of this work was to determine how capnometry measurements, in the form of end-tidal CO2 (ETCO2) and the perfusion index (PI), could improve the National Early Warning Score (NEWS2).

Methods: A secondary, prospective, multicenter, cohort study was undertaken in adult patients with unselected acute diseases who needed continuous monitoring in the emergency department (ED), involving two tertiary hospitals in Spain from October 1, 2022, to June 30, 2023.