Publications by authors named "A Samara"
Neutrophils and neutrophil extracellular traps (NETs) contribute to thrombosis and hyperinflammation in myeloproliferative neoplasms (MPN). High-density neutrophils (HDNs) and low-density neutrophils (LDNs) have recently been characterized as distinct neutrophil sub-populations with distinct morphological and functional properties. We aim to study the kinetics of NET formation and inhibition with interferon-α (IFNα) in neutrophils derived from patients with MPN as compared to matched healthy controls.
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- A 43-year-old woman developed both UVF and VVF after a total hysterectomy and initially tried conservative treatment, which didn't work.
- She then underwent a successful surgical procedure to correct the issues and has remained symptom-free for a year, highlighting the importance of recognizing and managing these rare fistula formations effectively.
Background: Early compromised first-permanent-molar (FPM) extraction can adversely affect occlusion. However, the current literature does not provide sufficient support for definitive early extraction outcome. This cohort study aimed to evaluate the pattern of post-FPM extraction spontaneous space closure and its pre-extraction indicators.
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- The study investigated how preoperative quality of life scores (EORTC QLQ-C30) relate to metrics like age and BMI in elderly patients undergoing colorectal cancer surgery.
- It included 118 patients over 65 with resectable cancer, revealing negative correlations between QLQ scores and age, as well as differences in scores based on the type of cancer (rectal vs colon).
- The findings suggest that lower preoperative QLQ scores are linked to longer recovery times and complications, indicating that these scores can predict postoperative outcomes in older patients.
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- The study aimed to replicate inflammatory conditions of human gingiva by using human gingiva fibroblast cells cultured under specific serum starvation conditions with various concentrations of lipopolysaccharides and interleukin 1β.
- Results showed that while P. gingivalis LPS did not increase inflammation markers, E. coli LPS and IL-1β did enhance the secretion of pro-inflammatory cytokines like IL-6 and TNFα, particularly when used together.
- The combination treatment mimicked gene expression changes and cytokine profiles observed in chronic inflammation, suggesting it could serve as a useful model for studying gingival inflammation in vitro.