Publications by authors named "A Salustri"

We sought to assess cardiac magnetic resonance derived left ventricular hemodynamic forces (HDF) in athletes compared to patients with hypertension. Sixty athletes and 48 hypertensive patients were studied. HDF were measured during the entire cardiac cycle, the systolic phase, suction, early LV filling, and atrial thrust.

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Article Synopsis
  • Peripheral artery disease (PAD) is a serious health issue globally, causing significant health problems and increasing mortality, prompting the need for more effective management approaches.
  • A study analyzing data from the Unified National Electronic Healthcare System (2014-2021) revealed a rising trend in PAD incidences, with 19,507 hospitalizations, predominantly affecting older adults and linked to several comorbidities.
  • The findings indicate that conditions like heart failure and acute myocardial infarction enhance mortality risks in PAD patients, reinforcing the need for urgent interventions in Kazakhstan to address this growing health concern.
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Background: Hemodynamic forces (HDF) analysis has been proposed as a method to quantify intraventricular pressure gradients, however data on its reliability are still scanty. Thus, the aim of this study is to assess the reliability of HDF parameters derived from cardiac magnetic resonance (CMR).

Methods: CMR studies of 25 athletes were analysed by two independent observers and then re-analysed by the same observer one week apart.

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Article Synopsis
  • - The study addresses the urgent need for new therapies against drug-resistant strains of tuberculosis (TB) by investigating the use of different functionalized graphene quantum dots (GQDs) in combination with standard TB drugs.
  • - While GQDs alone showed no significant antibacterial effects, combining NH-GQDs with amikacin resulted in a noticeable reduction in TB bacteria in infection models, indicating their potential to enhance existing treatments.
  • - The findings suggest that NH-GQDs could act as effective adjuvants to boost the efficacy of anti-TB drugs, signaling a promising avenue for improving drug delivery systems in TB therapy, although more research is necessary for clinical applications.
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Background: Physical activity contributes to changes in cardiac morphology, which are known as "athlete's heart". Therefore, these modifications can be characterized using different imaging modalities such as echocardiography, including Doppler (flow Doppler and Doppler myocardial imaging) and speckle-tracking, along with cardiac magnetic resonance, and cardiac computed tomography.

Main Text: Echocardiography is the most common method for assessing cardiac structure and function in athletes due to its availability, repeatability, versatility, and low cost.

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