From mathematics to medicine: A practical primer on topological data analysis (TDA) and the development of related analytic tools for the functional discovery of latent structure in fMRI data.

fMRI is the preeminent method for collecting signals from the human brain in vivo, for using these signals in the service of functional discovery, and relating these discoveries to anatomical structure. Numerous computational and mathematical techniques have been deployed to extract information from the fMRI signal. Yet, the application of Topological Data Analyses (TDA) remain limited to certain sub-areas such as connectomics (that is, with summarized versions of fMRI data).

Fitness-to-drive agreements after stroke: medical versus practical recommendations.

Background And Purpose: Physicians often struggle to screen out patients who are no longer fit to drive after stroke. The agreement between the recommendations of physicians and on-road assessors with regard to fitness to drive after stroke was investigated.

Methods: In this retrospective study, 735 patients with stroke underwent medical, visual and road tests at an official fitness-to-drive center of the Belgian Road Safety Institute.