Publications by authors named "A Saindane"
Article Synopsis
- Since 2006, neuroradiologists have restricted the use of gadolinium-based contrast agents (GBCAs) in patients with chronic kidney disease (CKD) to prevent nephrogenic systemic fibrosis (NSF), significantly reducing its occurrence.
- In 2023-2024, the American Society of Neuroradiology reviewed recent research on GBCA safety to update guidelines for MRI contrast use in CKD patients.
- The ASNR now recommends that Group II GBCAs can be safely used in CKD patients when necessary for diagnosis, and additional safety measures like checking renal function may be relaxed.
Background: White matter hyperintensities (WMHs) are strongly linked to cardiovascular risk factors and other health conditions such as Alzheimer's disease. However, there is a dearth of research on this topic in low-income countries and underserved populations, especially in the Democratic Republic of Congo (DRC) where the population is aging rapidly with increasing cardiovascular risk factors and dementia-related diseases. This study evaluates health factors associated with WMH in the elderly Sub-Saharan Africa (SSA), specifically Congolese adults.
View Article and Find Full Text PDFIntroduction: Recent diagnostic criteria for optic neuritis include T2-hyperintensity of the optic nerve (ON), even without associated contrast enhancement. However, isolated ON-T2-hyperintensity is a nonspecific finding found in any optic neuropathy or severe retinopathy. We applied the 2022 optic neuritis diagnostic criteria to a cohort of patients with noninflammatory optic neuropathy and ON-T2-hyperintensity in at least one eye, to assess the rate of optic neuritis misdiagnosis using these criteria.
View Article and Find Full Text PDFTEMPORAL LOBE HERNIATION AND CHIASMOPATHY DURING DOPAMINE AGONIST THERAPY FOR PROLACTINOMA.
Acta Endocrinol (Buchar)
February 2024
Background: Dopamine agonists (DA) are first line treatment for prolactinomas. Optic chiasm herniation can rarely occur during therapy, while brain herniation is very uncommon.
Case Reports: A 34 yo woman presented with headaches and vision changes.
Background/objectives: To report a series of patients with glaucoma and optic nerve abnormalities on magnetic resonance imaging (MRI) in at least one-eye, and to determine whether these findings correlate with the severity of glaucoma.
Patients And Methods: Retrospective study of all patients who underwent a brain/orbits MRI without and with contrast at our institution between 07/1/2019-6/30/2022. Patients with optic nerve T2-hyperintensity and/or MRI optic nerve atrophy in at least one-eye and a diagnosis of isolated glaucoma in at least one-eye were included.