Publications by authors named "A Saharia"
Background: The deceased donor shortage in the United States has led to increased utilization extended criteria donor (ECD) liver grafts. Centers often utilize ECD grafts in patients with low Model for End-Stage Liver Disease (MELD) scores, like patients with hepatocellular carcinoma (HCC). However, few studies have directly examined the outcomes of using ECD grafts in patients with HCC.
View Article and Find Full Text PDFHepatocellular carcinoma (HCC) is widely recognized as the predominant type of primary liver malignancy. Orthotopic liver transplantation (OLT) has emerged as a highly effective treatment option for unresectable HCC. Immunotherapies as neoadjuvant options are now being actively investigated in the transplant oncology era to enhance outcomes in patients with HCC.
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- * A targeted outreach program in Texas was implemented and led to an increase in referrals and waitlisting for LT among Hispanic patients, as well as a rise in the number of transplants received.
- * However, financial barriers emerged as a significant issue, with about 50% of the Hispanic patients unable to proceed with LT due to cost concerns, indicating the need for further research to address these financial obstacles.
Background: The COVID-19 pandemic has led to an increase in SARS-CoV-2-test positive potential organ donors. The benefits of life-saving liver transplantation (LT) must be balanced against the potential risk of donor-derived viral transmission. Although emerging evidence suggests that the use of COVID-19-positive donor organs may be safe, granular series thoroughly evaluating safety are still needed.
View Article and Find Full Text PDFBackground: Solid organ transplant (SOT) recipients are at risk of bloodstream infections (BSIs) with MDR organisms (MDROs).
Objectives: To describe the epidemiology of BSI in the year after several types of SOT, as well as the prevalence of MDRO infections in this population.
Methods: We conducted a single-centre, retrospective study of kidney, liver, heart, and multi-organ transplantation patients.